“Oxygen is the most vital element required for human life and is the key to good health. We can survive without water for a week, go without food for a month but we can only live a few minutes without oxygen. All body activities require oxygen.

It is through oxidation that the body generates heat and energy from its fuel (digested food etc) The process of oxidation enables the body to rid itself of toxins and microbes. The effective disposal of waste products from the body requires oxygen.

Our bodies consist of two-thirds water. Of that water 10% is in the blood and 90% in the lymph. The water in our bodies is in itself eight-ninths oxygen by weight; therefore our bodies are composed of over 50% oxygen!

The best way to optimise health is to oxygenate every cell in your body”. Oxidation is central to the metabolic, circulatory, respiratory, digestive, assimilatory and eliminatory processes of the body.

Oxygen purifies the blood; keeping it free of cellular waste build-up. Sufficient oxygen maintains the Immune System. Without oxygen, regeneration and rejuvenation of the body’s cells are impossible!”

OZONE THERAPY – The Safest Known Therapy

Ozone Therapy has been found to be an extremely safe therapy, virtually free from side effects!

In 1980, a study done by the German Medical Society for Ozone Therapy found the following:

First of all, to the problem of oxygen radicals and antioxidants. As with everything on our planet, both oxygen and antioxidants have two sides; the positive and the negative. On one side, free radicals will age us quicker; on the other side without them we have no immune system. It is not well known that oxygen is bound to our haemoglobin as a superoxide anion, so the oxygen in our breathing process is already there as a radical.

It’s the same with antioxidants. Antioxidants are often prescribed; to be taken along with the use of ozone. These are not simply opposites that cancel each other out, but rather, a thoughtful optimisation, since most antioxidants have very specific tasks. Vitamin E is active at the cell membrane. Vitamin C is itself a radical that can speed the electron flow through oxidation.

If ozone is taken for a long time at a high dose, it is wise to take Vitamin A as a preventative measure to prevent the lack of A and the problems associated with it.

In summary, both effects have their function and their place in a symbiotic relationship.

THE FREE RADICAL THEORY - Dr Deepak Chopra

In the mid-1950’s, Dr Denham Harman of the University of Nebraska theorized that free radicals are an important cause of aging at the cellular level.

This is believed to happen through a process called cross-linage, a chemical reaction that locks up the outer atomic shells of collagen. The cause of cross-linage is thought to be the tendency of free radicals to bind indiscriminately with many vital molecules in the body, including DNA. Cross-linkage is only one example of the damage free radicals can inflict. They can also split up molecules, garble information in cells, clog cell membranes, promote cancerous mutations, and impair the function of the mitochondria (the energy factories inside each cell).

Free radicals will attack almost any molecule; the extent of the damage they do is so wide that the free radical theory of aging has grown in popularity with each passing decade. Paradoxically, free radicals are necessary to life. A free radical is really a temporary stopping-point leading from one stable molecule to another. The normal life span of such unstable particles is thousandths of a second; millions of these fleeting molecules are emitted in every cell as it burns sugar with life-giving oxygen.

Why does the body produce free radicals? They are the natural product of any chemical reaction and they fit into the body’s overall balance. White blood cells use free radicals in hydrogen peroxide to destroy invading bacteria and viruses. In that role, the free radical’s tendency to latch onto anything in sight, save your life daily. To protect itself from any damage, every cell produces enzymes to neutralize free radicals. These free radical scavengers include superoxide dismutase and catalase.

In recent times, people have been urged to take large amounts of free radical scavengers in order to minimize cell damage. However, the eminent Japanese medical investigator Dr Yukie Niwa, himself a staunch proponent of the free radical theory, has demonstrated in the laboratory that dosing a culture of cells with these products does little to decrease free radical production. It would be still less effective for a person to swallow these scavengers, as most would be nullified by digestive juices long before they got to the cells they were meant to protect.

The whole life extension enterprise misses the point. The damage caused by free radicals is secondary, not causal. In its normal state, the body controls free radicals as a matter of course. Your body is not blindly fighting for its life against “bad” chemicals; such a notion is far too simplistic. If you could view a cell as it produces its myriad free radicals and myriad scavengers at the same time, you would see the two floating around in the same environment, not like loose cannons, but closely monitored and controlled by the cell. Both are kept in balance and used, as the cell requires a serene harmony.

It has not been shown that older people have necessarily higher levels of free radicals in their cells or lower levels of scavengers. Free radical damage is but a type of imbalance that can occur at the cellular level.

If the body’s generative powers are at an optimum, disorder and chaos do not attack a cell. One of the ways to maintain the body’s state of generative health is through exercise and providing a good supply of oxygen to the cells. By actually building muscle late in life, older people can significantly rejuvenate their whole physiology, reversing the metabolic decline we have come to see as normal. Physical fitness is also intimately linked to one’s general well-being and attitude.

Extract from “Contemporary Ozone Applications” - Kurt Donsbach

OZONE treatment is safe because of an enzyme coating that surrounds every cell. (which ozone does not penetrate) Bacteria and viruses have no such coatings and are oxidized on contact with ozone. Ozone also promotes the production of glutathione peroxidase, catalase, reductase and super-oxide dismutase which are enzymes forming the cell wall coating thus cellular immunity is enhanced.

Ozone also has a measurable benefit on the uptake and utilization of oxygen through improved glycolysis in red blood cells, reduction of clumping of red blood cells and the stimulation of mitochondrial respiration. This improved cellular respiration is invaluable in preventing cancer

In 1988 the following article started a mini-revolution in the alternative health care community because of its information on hydrogen peroxide and OZONE.

Extract from ‘THE CAUSE AND PREVENTION OF CANCER – Saul Pressman”

We now understand the chemical mechanisms of respiration and fermentation at the cellular level and due to the work of Dr. Otto Warburg, since 1926 we have known that when a cell is deprived of oxygen, down to about 40% of normal, its respiration is irreversibly damaged. This damage causes the cell to begin to ferment anaerobically producing carbon monoxide and lactic acid and only one-sixth of the energy of normal cellular aerobic oxidation takes place.
This oxygen deficiency (Hypoxia) can be caused by many factors. Poison may reach the cell and prevent it from taking up oxygen or the excretory duct of a gland becomes plugged up, as is in the case of breast cancer where the lymph gland becomes plugged up; whichever may be the cause the end result is the same. As soon as the oxygen level to the cell is reduced and the cell does not die the result will be cancer!

Frequent small doses of respiratory poison(s) are therefore more dangerous than a single large dose thereof. With a single large dose there is at least the chance that the cells will be killed rather than become cancerous.

“All carcinogens impair cellular respiration”. In this statement the word ‘carcinogen’ is an empty word. The continual search for more carcinogenic substances is an utter waste of time and money! This obscures the true cause of cancer; which is caused by oxygen starvation of the cell. It also prevents the successful treatment of cancer because of the misunderstanding of the cause of cancer.

To destroy cancer the introduction massive amounts of oxygen at cellular level is needed.

Ozone has the ability to prevent cancer. If sufficient oxygen is provided to the cells so that it never drops below 40% the cells will stay healthy. This will bar the need for chemical or radiation poisoning. It is as simple (and difficult) as that. Many people today are using ozone generators to keep their cellular oxygen levels high in order to prevent disease.

Ozone may be taken in many ways: You can drink ozonated water, introduce it into the ear, allow ozone to enter through the skin etc.

Several dozen AIDS patients have not only reversed their death sentences, but are back at work, completely free of the disease. They destroyed the virus in their blood by hyper-oxygenation, known in its various forms as oxygen therapy, bio-oxidative therapy or auto-haemotherapy.

This is a simple, inexpensive and very broad spectrum, healing process that many feel could force a complete overhaul of the medical industry. The two basic types of oxygen therapy are blood infusion and absorption of oxygen water (hydrogen peroxide) at very low concentrations.

It turns out that the AIDS virus cannot tolerate high levels of oxygen in their victim’s blood. Not only that, every other disease organism tested so far, apparently has the same weakness. Even cancer growths contract and disappear when the oxygen saturation is sufficiently increased in the fluids surrounding them, since they are anaerobic.

AIDS, herpes, hepatitis, Epstein Barr, cytomegalovirus and other lipid envelope viruses are readily destroyed by hyper-oxygenating the patient’s blood with OZONE. This was demonstrated by, among others, Dr. Horst Kief in Bad Hersfeld, Germany.

Dr. Kief has already cured a number of AIDS victims by drawing blood, infusing it with OZONE and returning it to the patient at regular intervals until all of the virus is gone. Dr. S Rilling of Stuttgart, and DR. Renate Viebahn of Iffezheim, are among the growing number of physicians who have obtained similar results with their patients

Ozone Blood Treatment

OZONE overcomes the AIDS virus by a fundamentally different process than that which is usually attempted with drugs. Instead of burdening the liver and immune system with more elaborate toxic substances, OZONE simply oxidizes the molecules in the shell of the virus.

As the OZONE molecules dissolve into the blood they give up their 3rd oxygen atom, releasing considerable energy that destroys all lipid-envelope viruses; apparently most other disease organisms as well while leaving blood cells unharmed.

It oxygenates the blood to a greater degree than is normally achieved, what with poor air and sluggish breathing habits. The disease will not return, as long as the patient maintains his blood in an oxygen-positive state.

If this is so, it follows that more the profit-fixated elements of the medical establishment will not be too thrilled about the recent surge of interest in oxygen therapies. The drug industry has expanded enormously since Word War II, while America’s level of health has dropped from the world’s highest to the lowest among the industrialised nations. It does look as if the bottom line has been money and not health, for a long time!”

MSM – Methyl Sulfonyl Methane

According to Saul Pressman MSM is extracted from DMSO by the process of adding another oxygen molecule to it so that is separates the dimethyl solvent from the sulphur. The sulphur left after this process is a biologically active sulphur, and it is the active ingredient in DMSO.

DMSO is a by-product of the timber industry. At one time Crown Zellerbach attempted to get rid of this ‘waste’ by spraying it on dirt roads to compact the earth. This caused problems, because animals of every description would come and lick it all up. The deer would lick six-inch potholes in the road. Dr Stanley Jacob of the Oregon Health Sciences University observed this and later identified this substance as DMSO, a healing penetrant that instantly soaks in through the skin and reduces pain. Eventually, Dr Jacob discovered that the active healing agent in DMSO is MSM.

MSM, the sulphur-bearing amino acid, is available to the cell and creates a flexible bond. Cells with insufficient MSM lose their ability to flex. Cells that have lost their ability to flex cause a wrinkle.

Sulphur has a vital relationship with protein, since sulphur is found in the amino acids methionine, cystine and cysteine. The sulphur-bearing amino acids are absolutely essential to health. Sulphur acts as an activator with all the B Vitamins, thiamine, biotin, Vitamin C and panthothenic acid. Sulphur aids the liver in bile secretion and helps maintain the overall body balance between acidity and alkalinity. Sulphur plays a role in carbohydrate metabolism, which is significant for controlling hypoglycaemia and diabetes. The lack of biological sulphur in the body results in low insulin production. Sulphur is a component of insulin, which is secreted by the pancreas for metabolising carbohydrates. Sulphur keeps hair, nails and skin healthy. In addition, sulphur plays an important part in cell respiration and assimilation. MSM is therefore essential and is thus found in all living organisms.

Medical research has proven that a minimal concentration of MSM is critical to function and structure, and that the concentration drops as time passes, directly contributing to aging. There has been extensive medical testing over the last ten years on the use of MSM in the diet. Some diseases considered irreversible, such as emphysema, have been overcome through use of supplemental MSM. Other diseases treated with excellent results are: pyorrhoea, skin burns and scars, eczema, psoriasis, dandruff, loss of hair, PMS, diabetes, hyperactivity, constipation, parasites, arthritis, carpal tunnel syndrome, candida, chronic fatigue syndrome, Epstein-Barr and low energy. MSM helps with the oxygenation of cells and free radical scavenging, and is thus anti-aging.

MSM occurs in fresh fruit and vegetables, raw milk, wheat grass juice and aloe vera. There is no toxic dose, and the body will excrete an-needed MSM.

Because it helps in the production of methionine, a basic liver enzyme, MSM is very important to proper digestion and assimilation of food. The liver cannot do its job of regulating enzymes and metering sugar and filtering out toxins properly without MSM. It is of little use to increase dosages of vitamins and minerals when they will just be excreted. Daily supplementation with MSM will ensure proper absorption of all nutrients with the corresponding betterment of health.

The Properties of Ozone and its Use in Industry and Technology

Since the 1960’s the increasing pollution of surface water through chemical substances has developed into a massive problem: subsequently, the highly disinfectant properties of ozone have come back under consideration, and the inclusion of an ozone processing phase in water treatment is gaining considerably in importance. The following properties make ozone one of the most important cleaning and disinfecting agents:

Macromolecules can be broken down as a result of its powerful oxidative effect.

Its capacity to react with compounds which cannot be broken down by biological agents or otherwise be integrated into the biological process or produce substances available for further processing, eg by bacteria, is of paramount importance.

Highly poisonous aromatics and heteroaromatics are destroyed, and can thus be removed by flocculation and filtered out.

And finally, its ability to kill all kinds of bacteria and viruses makes ozone one of the most important agents in the cleansing and (re) treatment of waste water.

Diabetic gangrene - p77

As additive therapy in diabetic gangrene, ozone therapy can be administered in the form of low-pressure O3 gas application under the suction cup according to localization, as described with the example of a heel ulcer.

The low-pressure method produces an acceleration in the healing process because, in the addition, the action of the ozone due to the sub atmospheric pressure causes a hyperemization and a “loosening” of the tissue, this insuring an improved diffusion of the ozone/oxygen gas mixture.

In exceptional cases, a normal pressure (normobaric) procedure can be applied; the transcutaneous ozone gas “bath” under an ozone-resistant plastic bag or foil.

As with all topical forms of O3 application, the simultaneous use of water is particularly important, as “dry” ozone is neither bactericidal nor does it have wound-healing properties.

A characteristic individual case in which an amputation at the upper thigh could be avoided is illustrated in Figure 20a and 20b hereunder: in this instance a female patient aged 68 who suffered from diabetes presented herself with an almost hand-sized ulcer on her heel and increasing difficulties, expressed for example by a maximum walking distance of only 30 to 80 meters (c 100 – 264 feet). After systemic and local ozone treatment in the transcutaneous immersion bag (“ozone bath”) a complete healing was achieved within 4 months; after dismissal from hospital, she was able to walk home without any signs of intermittent claudication (Rokitansky - 1982).

From the vascular surgery department of a hospital in Milan (Italy) Mattassi (1981) reported the results of treatment in over 113 cases with similar results.

Decubitus (bedsores and ulcers) – p73

The following quotation is a good introduction to the subject;

“As it is eminently practical, treatment with low-pressure ozone is suitable and indicated in every form of decubitus. The pronounced local hyperemization, produced both as a result of the low pressure and the effect of ozone on the open wound, contribute to accelerated healing. In fact, the method is far superior to the usually indicated circulatory stimulation via side positioning … Stages II through IV – ie skin defects – represent an absolute indication (for ozone); it is here that the two most important component factors of its effect, ie hyperemization and disinfection, can attain their greatest efficiency when applied below atmospheric pressure. This is of particular importance in the advanced stages III and IV: necroses are dissolved, and the wounds supplied with additional oxygen”
(Werkmeister 1995).

Here, Werkmeister discusses the results of a study he carried out in 214 cases of decubitus, and analyses treatment results over the period from 1975 through 1988, whereby a closing of the wound at a rate of 80 – 100% could be still obtained in 40% of participants (85 patients), all of whom were in a severe and/or advanced stage of the disease

In a group of 43 patients with acute stroke, extracorporeal ozone treatment of the blood was carried out with 3 000 µg in 50 to 100 ml of the patient’s own blood and, as far as possible, repeated over the following days. According to his or her condition, the patient then received corresponding further treatment in hospital.

Results:
With a typification of post-apoplectic syndrome in 3 stages, the following results could be obtained: in 37 patients bodily functions (including fine motor control) could be completely restored (T1); in 6 patients this function remained disordered, although the general motor function was retained (T2). All patients could be spared the third stage (T3) with its typical spastic conditions and severest forms of restriction. None of the patients died as a direct result of the stroke.

The nuclear resonance (NMR) pictures of 9 patients, compared with those of the patients not treated with medical ozone, are noticeable for a particularly small scar formation, from which a lower incidence of functional disorders in these patients becomes understandable.

Even if the number of cases is very small and these results need a clinically controlled study for confirmation, it is particularly noticeable that none of the patients could be classified as being “most severely” incapacitated.

Effect:
Due to the known immediate activation of cellular metabolism with a rise in ATP – as well as an increased 2,3-DPG level in the red blood cells – a rapid subsidence of the collateral edema is being discussed, which is accompanied by a repolarisation of those cells still capable of reactivation.

“In the inflammation cascade process, this means that stage 1, the edema formation is rapidly overcome. The 2nd stage with its activation of the tissue mast cells is thus shortened, and the 3rd phase ie collagen formation is reduced through insufficient activation. In the brain, the activation of astrocytes, which are responsible for postischemic scar formation, has also avoided the secondary zone of the stroke”
(Wasser - 1995)

Although the use of medical ozone is principally to be understood as a complementary therapeutic procedure, this principle is particularly valid when we turn to cancer therapy. The aim is to lengthen or maintain the effects of classical therapy, and to improve a patient’s well-being, life style and life quality.

With our new knowledge about the activation of immunocompetent cells by ozone, we now have a rationale for the complementary treatment of such conditions with ozone; a physiological release of cytokins in the microenvironment of different immunocompetent cells, and an increase or improvement in immune restoration is the result.

GERIATRIC CONDITIONS

General revitalization

In general, elderly persons respond very well to a treatment series of 6 to 10 autohaemotherapy sessions. This becomes quickly noticeable in the improvement of the patients’ general condition, and a specific revitalization.

Apart from activating immunocompetent cells and producing the corresponding cytokins, a metabolic activation of the red blood cells and the oxygen-releasing effect of ozone may also be held responsible for this improvement in relative well-being.

The activation of the organism’s own antioxidants and the consequently heightened antioxidative capacity of the organism could be of importance in delaying aging processes. If, for example, the activity of superoxide dismutase is increased an increased number of superoxide radicals are scavenged off, the formation of OH radicals is reduced, the degenerative processes thus slowed down.

The three most important effects of medical ozone application are of great importance in geriatric treatment and ozone biology, these being:

A small-scale study on this subject was initiated by Bocci in 1997: 34 patients (of which 17 suffered from the dry and 17 from the humid form of macular degeneration) received a series of 12 to 15 major O3 autohemotherapy treatments, whereby their visual acuity was tested over a period of 12 months. The results may be viewed as an encouragement to ophthalmologists with private practices – as well as those in clinics – to apply ozone therapy where invasive methods including laser therapy have proved to be unsuccessful.

In 8 of these patients, using superoxide dismutase as an example, changes in antioxidative effect were monitored; a practically continuous rise throughout a series of 15 major autohemotherapeutic applications can be seen, whereas the 2,3 DPG level showed no significant change.

Table 13 shows the results of a small pilot study conducted by Siemsen involving 38 patients.

Intraarticular and periarticular injections were found to be without any effect in 6 patients suffering from shoulder joint diseases. All other patients declared themselves to be at least satisfied with the treatment they received. According to the degree of severity of the disease involved, 1 to 20 injections with O3 at quantities of 50-to 500 µg ozone were used. The effect of ozone in intra-articular injection is discussed in Chapter 7.1 and Table 12.

In a large-scale study involving 326 patients, Riva reports on the successes obtained applying intraarticular knee injections with ozone/oxygen mixtures.

The major proportion, involving 242 patients, consisted of gonarthroses, of which 173 cases were without pronounced bone deformation (Group B) and 69 cases with bone deformations (Group C). It was found that, 3 to 4 weeks after the start of treatment, knee motility increased at the same rate as painfulness subsided (Group B). After the ozone therapy series, all patients received electrotherapy and massage. In the 69 patients of Group C, therapy success was delayed on account of the advances stage of the disease. Success was very limited in 47 of these patients after the first ozone injection series. A repeated application without additional therapy was not indicated; in these cases, steroids were additionally administered.

The most successful treatment was that of posttraumatic conditions of the knee (Group A) as observed in 84 patients; after the first ozone therapy series (twice a week with 20 ml and an ozone concentration of 10 µg/ml over a period from 5 to 6 weeks), 20% of these patients showed a complete restoration and needed no further therapeutical measures, not even after two years of monthly follow-up examination. In 80% of these patients, the knee was completely restored, so that electrotherapy and massage were excluded as further therapeutical measures (Riva 1996).

During the increase in glycolosis rates in the red blood cell under ozone application, the content of adenosine triphosphate also rises. An increase in ATP may be interpreted as a general activation of cell metabolism. It is possible that an ozone-induced rise in red blood cell ATP is responsible in stabilising the membrane potential and improving mechanical resistance (Bayer et al 1993). Minute quantities of extracellular ATP, which are considered as being possibly responsible for a series of rapidly occurring “ozone reactions”, such as vasodilation and availability of energetic reserves and inflammatory processes, are also being discussed (Wasser 1995).

2, 3 - Diphosphoglycerate – p 117

The deoxygenating substance 2,3-DPG plays a special part in the functionality of the red blood cell: as a transporter of oxygen, it has to deposit the oxygen (O2) it carries at the site where it is needed for further use. The affinity of haemoglobin to oxygen depends, however, a great deal on 2,3-DPG. In a healthy system this 2,3-DPG is present at the same molar quantities as haemoglobin itself is; in fact, it can slip into the center of the quartary structure of haemoglobin, at the same time releasing four oxygen molecules:

Hb (O2)4 + 2,3 DPG 2
Hb • 2,3 - DPG + 4 02

The 2,3-DPG lowers oxygen affinity by a factor of 26, or in other words, the oxygen-binding curve is increasingly shifted to the right as the 2,3-DPG content rises (Stryer - 1992).

The oxygen-releasing effect of ozone thus means the red blood cell can release its oxygen more easily, which results in improved oxygen supply to the peripheries. If this release of oxygen is reduced due to a 2,3-DPG content, which is too low or fluctuates too greatly (in diabetics for example), O3 application here means a refunctionalization of the RBC (red blood cells) – and thus an improved oxygen release.

The Action of Ozone on Immunocompetent Cells – p 125

As far as the white blood cell (WBC) status is concerned, an immunomodulatory effect of ozone on the basis of empirical data has been under discussion for decades now. Thus, the improved well being of elderly patients, or cancer patients, after a series of treatments with ozone is attributed to its immunoactivating effect. Since Bocci and his team investigated ozone and its effect on immunocompetent cells, we now have exact results contributing to our understanding as to how ozone acts in the human organism; in the meantime a large number of publications on this subject has become available.

Cytokine Induction – p 126

Among the immunocompetent cells, the T4 lymphocytes (TH1) occupy a key position. Activated by the macrophages they produce cytokins, which initiate intercellular communication in their function as messengers. For example we find interleukin-2, which is responsible for a large number of functions such as the activation of more R4 lymphocytes to become cytotoxic killer cells, or of B-lymphocytes to produce specific antibodies. In this way, activated helper cells set off a whole cascade of immune reactions.

In treated, whole blood, ozone is in a position to assume the activation of immunocompetent cells directly, ie it can produce a specific immunoactivation.

Properties and Effect – p 148 and 149

Medical ozone has highly pronounced bactericidal, fungicidal and virostatic properties, and is thus widely used in disinfecting infected wounds, as well as in bacterially and virally produced diseases.

Its ability to stimulate the circulation is used in the treatment of circulatory disorders and makes it valuable in revitalising organic functions.

When administered at low concentration, the organism’s own resistance is mobilised, ie ozone (re) activates the immune system.

As a response to this activation through ozone, the body’s immune cells produced special messengers called cytokins (including important mediators such as interferones or interleukins). These inform other immune cells, setting off a cascade of positive changes throughout the immune system, which is stimulated to resist diseases for example. This means that the application of medical ozone is extremely useful for immune activation in patients with a low immune status and/or immune deficit.

Circulatory Disorders – p 151 and 152

In this therapeutical category, ozone shows its greatest efficacy in arterial circulatory disorders characterised by a sensation of heaviness and coldness and/or pains in the legs, especially when walking. In fact, patients affected are only able to cover relatively short distances (well known as smoker’s leg or intermittent claudication) – a signal of alarm. In fact this form of treatment has avoided amputations in a large number of clinically recorded cases.

Geriatric (age-related) Conditions
Thanks to its general revitalising capacity (including nerve and brain functions), ozone can be used successfully for poor concentration, forgetfulness, general reductions in mental and physical performance, insecurity in walking (balancing problems) and clinical dizziness or vertigo. Elderly persons in particular experience an improvement in well-being and life quality.

Macular Degeneration
O3 is also used to exert a positive influence on weak sight (decreasing visual acuity) due to age-related retinal detachment.

Intestinal Conditions
Inflammatory conditions of the large (eg colitis) and small intestines, fistulas and proctitis (inflammation of the rectum). A local application of ozone gas introduced via insufflation provides rapid relief to many such unpleasant and inconvenient conditions.

Virus-produced Diseases
A series of clinical trials and pharmacological studies are able to demonstrate the good success rate of ozone treatment in painful, virus-produced conditions such as hepatitis and herpes. The term of the diseases is greatly shortened, healing is more efficient, and the patient is rapidly restored to his/her original well-being.

Rheumatism/Arthritis
In the whole complex of “rheumatic/arthritic” conditions, all of which attack the skeletal and locomotory systems to a varying degree, ozone successfully causes pain and inflammation to subside. Repeated treatment can even produce permanent restoration!

Ozonized olive oil – p 62
In Germany and a number of other European countries, ozonized olive oil can be obtained on prescription from a number of pharmacies in different preparation forms. In contrast to ozone solo, which has a very short half life, this ozonized product can be stored for a considerable time when specific precaution are taken; its active ingredients are ozonides and peroxides (Washuttl/Viebahn 1982-1987).

Compared with directly applied ozone, its fungicidal and bacterial effects are slower; the inactivation of micro-organisms in ozonized water, for example, takes place within seconds, whereas ozonized olive oil requires a number of hours to produce the same effect due to its peroxidic products.

Thanks to its fungicidal and bactericidal effect, particularly in extensive fungoid/mycotic skin infections, ozonized olive oil is used locally for disinfecting lesions and promoting their healing.

The application of ozonized olive oil – p 80
Due to the low reactivity of ozonides and peroxides in an aqueous medium, the fungicidal and bactericidal properties of ozone do not become noticeable until after a specific latent period. Ozonized olive oil is thus especially useful when combined with transcutaneous (“O3 bath”) ozone treatment and a simultaneous application of ozonized treatment is reserved to the private practice or clinic, ozonized olive oil can be used at home for further treatment, to complement and continue the effect of O3 applied by a different method.

Animal Model
In an animal experiment as model, Schulz was able to demonstrate its wound-healing effect in the case of both mechanical and thermic lesions; rapid wound healing, a hyperemizing effect (ear skin temperatures) and, histologically, a “more mature” granulation tissue were found.

Use in gynaecology: vaginal candidiasis
In 20 patients, “recurrent candidal vaginitis: was evidenced in bacteriological cultures (average age 26 years, complaints; fluor vaginalis pruritus vaginae);they all received treatment with ozonized olive oil for 5 days, as a previous treatment had been unsuccessful (Clotrimazol).
Already on the 2nd day of treatment, there was a noticeable improvement in subjective complaints so that, after the 5th day of treatment, all patients were subjectively free of complaints; an investigation of native samples only proved to be candida positive in 2 of the total (2) cases.
The elegant advantage of this treatment is that it can be administered by the patients themselves when at home. (Schonbauer et al.).

Circumscribed osteitis (ostitis circumscripta):
In a controlled study by Filippi, 65 patients suffering from circumscribed osteitis in the lower jaw occurring after surgical removal of a wisdom tooth received local treatment with ozonized olive oil versus the conventional chlorphenol/ camphor/menthol method.
In the context of both single and combined therapy, a more markedly rapid therapy success was obtained on application of the ozone-enriched preparation, and the duration of treatment could be shortened on average by more than 2 days when ozonized olive oil was used.
Recommendation:
Ozonized olive oil should only be applied locally, and spread in the form of a thin layer over the affected area once to twice per day. Bandages or drainage application should be changed daily. The characteristic smell of ozone may prove to be slightly irritating when it is applied in the mouth and facial regions.

External Ulcers and Skin Lesions - p72
The fungicidal, virucidal and bactericidal properties of ozone make the medical ozone/oxygen mixture a valuable therapeutic agent in the cleaning and disinfection of wounds; its specific, stimulant effect on the circulatory system improves and accelerates wound healing. Using a radiation ulcer as his model, Werkmeister was able to demonstrate the rapid wound-cleansing effect of ozone in a very impressive manner.

Ozone therapy is particularly indicated in all infected wounds, in dermatomycoses, weeping eczemas, ulcus cruris, decubitus ulcers, and all badly healing wounds.

Chronic bad wound healing after irradiation – p76
A variation on the low-pressure treatment described above is reported by Sader, who successfully used a suction cap for chronically disturbed and/or delayed wound-healing processes in the maxillary region.

Especially in patients following radiation therapy for malignant tumours in the buccal, maxillary and facial areas, considerable secondary problems and/or delays in would healing occur.

Thus in order to avoid a complete or even a partial resection/excision in the maxillary region, Sader, conducted a “clinical pilot study in 11 previously irradiated patients with superficial osteoradionecrosis, in whom no rapid healing could be obtained with conservative and minimal surgical therapy methods”. Other complementary therapeutic measures, such as low-pressure ozone application, were not accessible to all patients – and those suffering from ostitic changes at a deeper level were also excluded.

Using local low-pressure ozone gas therapy, it was here possible to achieve healing in 9 out of 11 cases which, in the light of their severity – even if we are here dealing with a purely case related model – is remarkable; in other words, active O3 support protected these patients from the massive resection of the lower jaw which would otherwise have had to take place, involving the dreaded esthetic and functional problems.

Ulcus cruris - p78
In topical ozone treatment as a complementary/additive measure for ulcus cruris, we should work in a pressure free system and not with the low-pressure ozone “boot”, using either plastic bag or applying ozonized water. In principle, the method is as follows: first treat the super infected ulcer with high ozone concentration in a transcutaneous gas bath (ozone immersion system), and then – after wound cleansing accompanied by incipient epithelialization and granulation - drastically reduce the concentration to values around 20ug/ml, or change over to ozonized water alone. Here, the ozonized water combines the advantages of providing an optimum environment for O3 and of stimulating (and thus accelerating) the wound healing process when applied at a concentration range of 20ug per ml water.

Treatment of burns – p79
Medical ozone/oxygen mixtures can be used very effectively in severe burns. In the presence of absolutely sterile water, first of all use the transcutaneous gas bath at high O3 concentration to prevent possible super infections; then reduce the concentration to the lower levels ideal for wound healing; this process can be completed to great advantage by applying compresses with ozonized water. During the first week, treatment on a day-today basis is mostly indicated; the frequency can then be reduced to three or two treatment sessions per week. The special advantage of this method is seen in the rapid subsidence (decongestion) of edemas, swelling etc, and quick pain relief.

Oxygen therapy is an umbrella for a number of closely related cutting edge therapies that seek to promote healing by flooding the body with oxygen. Ozone therapy is probably the most powerful of the Oxygen therapies.

Poor immunity, constant tiredness, colds and flu’s, and low vitality are primarily caused by oxygen starvation – people are tired, low in energy, susceptible to viruses and so on because their bodies are starved of oxygen. People with asthma and bronchitis are starved of oxygen and usually respond well to this therapy. Headaches and migraine sufferers also report benefits (are these conditions caused by lack of oxygen to the brain?). What we do know is that when the body is flooded with oxygen, people consistently report that their health problems go away.

Ozone therapy can be beneficial to most chronic illnesses as well as some acute infections. Today, over 7 000 German Physicians use ozone therapy in their offices to perform 6 million chronic illness treatments annually.

In the last several years there have been laws passed in 10 states to protect their physicians from state medical board actions for using controversial therapies. These laws allow non-FDA (Food and Drug Administration in America) approved therapies (such as ozone therapy) to be used between a physician and his patient as long as “duel-consent” is in place and the patient has been thoroughly informed. The states that have passed these laws are: